Dr. Pankaj Singh

Research, Innovation & Clinical Leadership

Clinical innovation. Research. Healthcare transformation.

For more than two decades, my work has focused on one question: how can we transform fragmented healthcare into intelligent, evidence-driven systems that improve outcomes for millions of patients?

Rather than pursuing research for publication alone, I focus on translating scientific evidence into practical clinical workflows that improve patient care, physician efficiency, and healthcare economics.

Today, this work extends across sleep medicine, temporomandibular disorders, chronic pain, oral-systemic health, clinical AI, and healthcare informatics.

A career at the intersection of

  • Clinical practice
  • Research
  • Technology
  • Education
  • Healthcare operations

Areas of research

Four research pillars.

Precision dental sleep medicine

Developing AI-assisted methods for identifying undiagnosed obstructive sleep apnea through dental practices.

Focus areas include

  • Risk stratification
  • Digital phenotyping
  • Treatment selection
  • Longitudinal outcomes
  • Population screening

Orofacial pain & TMJ disorders

Advancing multidisciplinary diagnosis of complex facial pain through evidence-based clinical pathways integrating dentistry, neurology, ENT, pain medicine, and behavioral health.

Research includes

  • Differential diagnosis
  • AI-supported clinical reasoning
  • Standardized documentation
  • Outcome tracking

Clinical artificial intelligence

Designing explainable AI systems that augment — not replace — clinical judgment.

Current interests include

  • Diagnostic support
  • Clinical decision engines
  • Automated documentation
  • Predictive analytics
  • Precision treatment recommendations

Digital health

Creating scalable technology platforms that improve access to specialty care while reducing provider burden.

Research includes

  • Telehealth
  • Clinical workflow automation
  • EHR optimization
  • Reimbursement optimization
  • Population health

Appnea™

Clinical
intelligence.

Translational research

Translating research into clinical practice.

A significant focus of my work has been transforming published evidence into practical systems that clinicians can use every day. This philosophy ultimately led to the development of Appnea™, an AI-enabled clinical platform designed to standardize and scale evidence-based diagnosis and management of dental sleep medicine and temporomandibular disorders.

Rather than functioning as another electronic health record, Appnea serves as a clinical intelligence platform that integrates diagnostic reasoning, documentation, treatment planning, patient education, outcomes measurement, and reimbursement workflows into a single ecosystem.

The goal is simple: improve patient outcomes while reducing clinician burden.

Clinical leadership

Building the future of dental sleep medicine.

As healthcare shifts toward integrated, value-based care, dentistry will play an increasingly important role in identifying systemic disease. My work focuses on helping organizations build comprehensive dental sleep medicine and orofacial pain programs.

Programs combine

  • Clinical excellence
  • Standardized protocols
  • Physician collaboration
  • AI-enabled decision support
  • Measurable patient outcomes

Designed to scale across

  • Academic institutions
  • Multi-specialty practices
  • DSOs
  • Integrated healthcare systems

Academic vision

Advancing academic medicine.

The future clinician must be equally comfortable interpreting research, practicing evidence-based medicine, and leveraging intelligent technologies that enhance patient care.

I actively seek collaborations with universities and academic medical centers committed to shaping this future.

The next generation of dental education must integrate

  • Clinical excellence
  • Research
  • Artificial intelligence
  • Healthcare informatics
  • Interdisciplinary medicine
  • Population health

Selected contributions

Four lines of contribution.

Clinical research

Peer-reviewed publications in

  • Dental sleep medicine
  • Orofacial pain
  • Airway medicine
  • TMJ disorders

Technology innovation

Founder, CEO, and chief scientific officer of Appnea™

AI-powered clinical platform for

  • Dental sleep medicine
  • Orofacial pain
  • Intelligent clinical documentation
  • Decision support

Education

International lecturer, faculty educator, and clinical mentor

Professional education in

  • Oral surgery
  • Oral medicine
  • Sleep medicine
  • TMJ and orofacial pain
  • Biomedical engineering
  • Artificial intelligence
  • Practice integration

Healthcare leadership

Advisor, clinical director, and healthcare strategist

Focused on

  • Digital transformation
  • Clinical quality
  • AI implementation
  • Provider adoption

Strategic advisor & board leadership

Bridging clinicians, engineers, and enterprise.

  • Founder and chief scientific officer of Appnea
  • Clinical AI thought leader
  • Healthcare technology innovator
  • Experience building scalable clinical platforms
  • Deep expertise in regulatory, reimbursement, and workflow adoption
  • Ability to bridge clinicians, engineers, investors, and enterprise customers
  • Strategic advisor for digital health, AI, and healthcare transformation
  • Experience translating clinical needs into commercially viable products

A vision for the future

Healthcare is entering an era where artificial intelligence will not replace clinicians — but will fundamentally change how clinicians deliver care.

The opportunity is not merely to digitize healthcare, but to redesign it around intelligence, interoperability, and measurable patient outcomes.

My mission is to help build that future through rigorous science, thoughtful innovation, interdisciplinary collaboration, and technologies that empower providers while improving the lives of patients.